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Sucralfate

Why has my veterinarian prescribed this medicine?

Sucralfate is used to treat oral, esophageal, gastric and duodenal ulcers. It may also be used to prevent non-steroidal anti-inflammatory induced ulceration. This medication forms a barrier over the ulcer, which protects the ulcer from the acid of the stomach and allows it to heal.

How do I give this medication?sucralfate-1

"Give this medication on an empty stomach, 1 hour before meals or 2 hours after meals."
  • Give this medication to your pet as directed by your veterinarian. READ THE LABEL CAREFULLY.
  • If the medicine is a liquid, measure the dose with reasonable care.
  • Give this medication on an empty stomach, 1 hour before meals or 2 hours after meals.
  • Try to give this medication at about the same time(s) each day.
  • DO NOT give the pet more medicine than directed.
  • DO NOT give the medicine more often than directed.
  • DO NOT stop giving this medication to your pet unless directed by your veterinarian. Call your veterinarian ahead of time if your pet needs a refill.
  • DO NOT give with other medications as absorption of other drugs will be decreased.
  • Try not to miss giving any doses.

What do I do if I miss giving a dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give the pet two doses at once.

How do I store this medicine?

  • Keep this medicine out of reach of children.
  • Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight.
  • Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

What are the potential side effects?

  • Side effects are rare.
  • Occasionally, constipation has occurred.
  • Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Are there any possible drug interactions?

"Separate the administration of sucralfate and these drugs by 2 hours."
  • Make sure to tell your veterinarian if you are giving your pet any other medication or supplements.
  • Quite often, your veterinarian may prescribe two different medications, and sometimes a drug interaction may be anticipated. If this occurs, your veterinarian may vary the dose and/or monitor your pet more closely.
  • The following drugs can potentially interact with sucralfate: cimetidine, tetracycline, phenytoin, digoxin, and antacids. Separate the administration of sucralfate and these drugs by 2 hours.
  • Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Jul 28, 2016.